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Strengthening The Intestinal Barrier May Prevent Cancer In The Rest Of The Body
A leaky gut may be the root of some cancers forming in the rest of the body, a new study published online Feb. 21 in PLoS ONE by Thomas Jefferson University researchers suggests...
Wed, 22 Feb 2012 02:00:00 PST - Source:MedNewsToday

Better Understanding Of Cancer Drugs Following Discovery Of Cell Energy Sensor Mechanism
Johns Hopkins and National Taiwan University researchers have discovered more details about how an energy sensing "thermostat" protein determines whether cells will store or use their energy reserves. In a report in Nature, the researchers showed that a chemical modification on the thermostat protein changes how it's controlled...
Wed, 22 Feb 2012 02:00:00 PST - Source:MedNewsToday

Drugs That Affect Serotonin Signaling May Combat Bone Loss
Scientists have long known that calcium leaches from the bones both during lactation and in certain types of cancer. The driver behind these phenomena is a molecule called parathyroid hormone related protein (PTHrP), which is secreted by the mammary glands. The signal that regulates the secretion of PTHrP, and where this other unknown molecule exerts its influence, has remained a mystery...
Wed, 22 Feb 2012 01:00:00 PST - Source:MedNewsToday

For Patients With Advanced Hepatitis C, The Benefits Of Treatment Outweigh The Costs
A towering $60,000 bill, a year of fierce, flu-like symptoms and a running risk of depression are among the possible costs of two new hepatitis C treatments. But according to Stanford University health policy researchers, they might be worth it...
Wed, 22 Feb 2012 00:00:00 PST - Source:MedNewsToday

Reformulated Imatinib Eliminates Morphine Tolerance In Lab Studies
By reformulating the common cancer drug imatinib (GleevecĀ®), researchers have eliminated morphine tolerance in rats - an important step toward improving the effectiveness of chronic pain management in patients, according to researchers at The University of Texas MD Anderson Cancer Center. Narcotics such as morphine are a mainstay of chronic pain treatment...
Wed, 22 Feb 2012 00:00:00 PST - Source:MedNewsToday

Potential For Development Of Tailor-Made Anticancer Agents Following Mapping Of Protein Inhibitors
A team of researchers at Karolinska Institutet has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism behind putative side effects of the so-called PARP inhibitors, and can play an important role in the development of novel tailor-made cancer drugs...
Wed, 22 Feb 2012 00:00:00 PST - Source:MedNewsToday

Cancer Cells Destroyed By Blocking Telomerase But Resistance, Progression Provoked
Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive and spread, scientists report in Cell...
Wed, 22 Feb 2012 00:00:00 PST - Source:MedNewsToday

Possible New Target For Cancer Therapy - Energy Network Within Cells
Mitochondria, tiny structures within each cell that regulate metabolism and energy use, may be a promising new target for cancer therapy, according to a new study. Manipulation of two biochemical signals that regulate the numbers of mitochondria in cells could shrink human lung cancers transplanted into mice, a team of Chicago researchers report in the journal FASEB...
Wed, 22 Feb 2012 00:00:00 PST - Source:MedNewsToday

Identification Of 'Stealth' Properties Of Cancer-Causing Genetic Mutations
Scientists have discovered that cancer-causing genetic mutations have better-disguised electronic signatures than other mutations - a trait which could help them fly under the radar of the body's defence mechanisms...
Wed, 22 Feb 2012 00:00:00 PST - Source:MedNewsToday

Drug Combo Kills Pancreatic Cancer Cells
Combining gemcitabine with MRK003, an experimental drug, triggers a chain of events leading to pancreatic cancer cell death, researchers from Cambridge reported in the Journal of Experimental Medicine. The researchers explained that when the two drugs are combined, the effect of each one is multiplied, thus intensifying the destruction of pancreatic cancer cells...
Tue, 21 Feb 2012 09:00:00 PST - Source:MedNewsToday

Cancer Evolution Discussed At Prestigious Conference
Professor Mike Stratton, Director of the Wellcome Trust Sanger Institute, talked about 'the evolution of the cancer genome' at the prestigious 2012 American Association for the Advancement of Science annual meeting. The AAAS annual meeting is one of the world's most widely recognized science events...
Tue, 21 Feb 2012 01:00:00 PST - Source:MedNewsToday

A Model For Collaboration - Indiana Clinical And Translational Science Institute HUB
At a time when medical research increasingly requires collaboration by large numbers of busy people, the Indiana Clinical and Translational Science Institute HUB offers a model for using advanced information technology to link scientists, health providers, community partners and others for the purpose of accelerating clinical and translational research...
Tue, 21 Feb 2012 01:00:00 PST - Source:MedNewsToday

A Promising Novel Therapeutic Target In Cancer - The USP15 Biological Thermostat
After years studying the molecular bases of glioblastoma - the most common brain tumor and one of the most aggressive of all cancers, the group led by Dr...
Tue, 21 Feb 2012 01:00:00 PST - Source:MedNewsToday

Women May Be At Increased Cancer Risk Following Vitamin B And Omega-3 Supplementation
Women with a previous history of cardiovascular pathologies seem to have a higher cancer risk after five years of Vitamin B and omega-3 supplementation. The research is published in detail in the Archives of Internal Medicine...
Tue, 21 Feb 2012 00:00:00 PST - Source:MedNewsToday

Smokeless Tobacco Substitutes Save Lives
Substituting smokeless tobacco products can save smokers' lives, and there is a scientific foundation that proves it. That is the message Brad Rodu, D.D.S...
Tue, 21 Feb 2012 00:00:00 PST - Source:MedNewsToday

New Approach To Fighting Cancer - New Combo Of Chemo And Malaria Drug Delivers Double Punch To Tumors
Blocking autophagy - the process of "self-eating" within cells -- is turning out to be a viable way to enhance the effectiveness of a wide variety of cancer treatments. Specifically, blocking the action of an acidic inner cell part, which acts like a stomach and chews up proteins for recycling, is the main attack strategy, says Ravi K...
Tue, 21 Feb 2012 00:00:00 PST - Source:MedNewsToday

Health Behaviors Worse Among Female Cancer Survivors
Women who survive cancer receiving mammography screening have "worse health behaviors", than those who had never had cancer and receiving mammography screening, according to a study by researchers at Moffitt Cancer Center in Tampa, Fla., and the Mayo Clinic in Rochester, Minn. The study was published in the American Journal of Clinical Oncology...
Mon, 20 Feb 2012 09:00:00 PST - Source:MedNewsToday

"DNA Origami" Robots Target Cancer Cells
Using a technique called "DNA origami", US scientists have made programmable molecule-transporting nanorobots that can seek out particular cell targets and deliver specific instructions for them to follow. One example of such use could be to tell cancer cells to destroy themselves. The researchers write about their findings in Friday's online issue of Science...
Mon, 20 Feb 2012 01:00:00 PST - Source:MedNewsToday

Major Breakthrough In Nanosurgery And The Fight Against Cancer
Researchers at Polytechnique Montreal have succeeded in changing the genetic material of cancer cells using a brand-new transfection method. This major breakthrough in nanosurgery opens the door to new medical applications, among others for the treatment of cancers...
Mon, 20 Feb 2012 00:00:00 PST - Source:MedNewsToday

New Paths To Treat Cancer, Other Diseases, With The Help Of Video Games
The cure for cancer comes down to this: video games. In a research lab at Wake Forest University, biophysicist and computer scientist Samuel Cho uses graphics processing units (GPUs), the technology that makes videogame images so realistic, to simulate the inner workings of human cells...
Mon, 20 Feb 2012 00:00:00 PST - Source:MedNewsToday

Virus' Coats Used In Nano-Technology To Fool Cancer Cells
While there have been major advances in the detection, diagnosis, and treatment of tumors within the brain, brain cancer continues to have a very low survival rate in part to high levels of resistance to treatment...
Mon, 20 Feb 2012 00:00:00 PST - Source:MedNewsToday

New Guiding Principles For Cancer Genomics: Understanding Chromosome Reshuffling, Looking To The Genome's 3D Structure
That our chromosomes can break and reshuffle pieces of themselves is nothing new; scientists have recognized this for decades, especially in cancer cells. The rules for where chromosomes are likely to break and how the broken pieces come together are only just now starting to come into view...
Mon, 20 Feb 2012 00:00:00 PST - Source:MedNewsToday

Researchers Test Nanoscale Carbon Clusters For Chemotherapy
A mixture of current drugs and carbon nanoparticles shows potential to enhance treatment for head-and-neck cancers, especially when combined with radiation therapy, according to new research by Rice University and the University of Texas MD Anderson Cancer Center. The work blazes a path for further research into therapy customized to the needs of individual patients...
Mon, 20 Feb 2012 00:00:00 PST - Source:MedNewsToday

Living Model Of Brain Tumor
Brown University scientists have created the first three-dimensional living tissue model, complete with surrounding blood vessels, to analyze the effectiveness of therapeutics to combat brain tumors. The 3-D model gives medical researchers more and better information than Petri dish tissue cultures...
Mon, 20 Feb 2012 00:00:00 PST - Source:MedNewsToday

Novel Technology Could Potentially Seek Out Cancer Cells And Cause Them To Self-Destruct
Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have developed a robotic device made from DNA that could potentially seek out specific cell targets within a complex mixture of cell types and deliver important molecular instructions, such as telling cancer cells to self-destruct...
Sun, 19 Feb 2012 00:00:00 PST - Source:MedNewsToday





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